Search / io.github.helena-bioinformatics/folklore
protogridR0· no sign-inBioinformatics MCP for genomic variant interpretation, gene-disease evidence and literature.
v1.5.0 · active · repository · website · descriptor JSON · versions
{
"mcpServers": {
"folklore": {
"type": "http",
"url": "https://api.helena.bio/folklore/v1/mcp"
}
}
}claude mcp add --transport http folklore https://api.helena.bio/folklore/v1/mcp[mcp_servers.folklore]
url = "https://api.helena.bio/folklore/v1/mcp"
{
"$schema": "https://opencode.ai/config.json",
"mcp": {
"folklore": {
"type": "remote",
"url": "https://api.helena.bio/folklore/v1/mcp",
"enabled": true
}
}
}{
"mcpServers": {
"folklore": {
"type": "http",
"url": "https://api.helena.bio/folklore/v1/mcp"
}
},
"deeplink": "cursor://anysphere.cursor-deeplink/mcp/install?name=folklore&config=eyJ0eXBlIjoiaHR0cCIsInVybCI6Imh0dHBzOi8vYXBpLmhlbGVuYS5iaW8vZm9sa2xvcmUvdjEvbWNwIn0%3D"
}{
"servers": {
"folklore": {
"type": "http",
"url": "https://api.helena.bio/folklore/v1/mcp"
}
}
}{
"mcpServers": {
"folklore": {
"httpUrl": "https://api.helena.bio/folklore/v1/mcp"
}
}
}extensions:
"folklore":
enabled: true
name: "folklore"
type: streamable_http
uri: "https://api.helena.bio/folklore/v1/mcp"
timeout: 300
protocol.modernsupports 2026-07-28 (server/discover)protocol.statelessanswers without a sessionprotocol.transportstreamable HTTPprotocol.list_ttltool list is cacheable (ttlMs 86400000)auth.prm, auth.as_metadata, auth.cimdno remote uses OAuthauth.secret_in_urlno templated URLtools.descriptionsevery tool has a descriptiontools.description_lengthdescriptions are concisetools.schemasevery tool has an object input schematools.annotations7 of 7 tools declare readOnlyHint or destructiveHinttools.directory_hintsevery tool declares readOnlyHint, destructiveHint, idempotentHint and openWorldHinttools.token_costabout 2,289 tokens to load every tooltools.api_dumptools are not a one-to-one API dumpstability.changesno tool changes in 30 daysstability.rug_pullno tool changed its meaning under the same namedeps.known_vulns, deps.mcp_sdk_version, deps.resolvableno npm or PyPI packageNo tool definition changes recorded. A server's first observation is its baseline; later probes record what changes.
Checks run on what our credential-free, read-only probes observe; tools are never called and no code audit is performed. How it is computed.
+repository +namespace-matches-repo +website +reachable +uptime-99% ~updated-38d-ago
Derived from observable signals (official registry feed and our own credential-free probes); no code audit performed. How it is computed.
| remote | auth | reachable | uptime 30d | p50 | protocol | last ok |
|---|---|---|---|---|---|---|
https://api.helena.bio/folklore/v1/mcp streamable-http | none | yes | 99% | 483 ms | 2026-07-28 | 2026-10-19 |
get_gene_disease_associationsread-only | Find diseases associated with one human gene for bioinformatics and clinical genomics research. Accepts an exact gene symbol or HGNC identifier. Returns ClinGen gene-disease validity assertions, relation-specific inheritance, source reports and snapshot provenance. Preserves conflicting and limited assertions. Gene-disease validity is not variant pathogenicity or a patient diagnosis. Use only a public gene identifier; no patient or case data. Results require professional review. |
get_publication_detailsread-only | Retrieve the complete public bibliographic record for one PMID from Folklore's PubMed-derived genetics corpus. Returns the full abstract, authors, journal metadata, publication and MeSH terms, gene and variant mentions, retraction status, and PubMed/PMC links. Use after literature search when a user asks to inspect a specific publication. This is read-only professional literature evidence and contains no patient context. |
search_disease_genesread-only | Find human genes associated with a disease for genomic analysis and rare-disease research. Accepts an exact MONDO identifier or a disease-name search. Returns matching ClinGen gene-disease validity assertions with inheritance, source reports and snapshot provenance. Name searches may match multiple diseases; preserve their distinct identities and do not infer a diagnosis. Use only a public disease name or identifier; no symptoms, patient or case data. Results require professional review. |
search_literature_corpusread-only | Semantically search the public scientific Literature Corpus by a natural-language question. A question may include one or more PMID, DOI or PMCID references; those publications become exact anchors for finding related experiments, evidence and concepts across the corpus. Also accepts genes, variants, phenotypes, HPO and OMIM concepts. Include every known publication identifier in the query when the user asks to compare papers or find work related to a specific paper. Returns source-linked evidence candidates for professional review, not diagnoses, causality claims or treatment recommendations. |
search_variant_evidenceread-only | Interpret this variant, explain what this HGVS means, or review this VUS. Use for human genomic variant analysis within bioinformatics workflows, including review of an already identified WGS/WES variant. Use when a user asks to classify or interpret pathogenicity, review a VUS, check available ClinVar assertions or population-frequency evidence, or resolve a variant notation. Classify, interpret or resolve one public GRCh38 germline SNV or simple indel smaller than 50 bp. Accepts coordinates, genomic/coding/protein HGVS, SPDI or rsID. Returns normalized variant identity, automated ACMG/AMP decision support, evidence, provenance and explicit limitations. This is variant-level decision support for professional review. It does not evaluate patient context and must not be presented as a diagnosis or treatment recommendation. Never choose a candidate when resolution is ambiguous. |
search_variant_literatureread-only | Resolve one public GRCh38 germline variant and retrieve relevant publications from Folklore's PubMed-derived genetics corpus. Exact variant mentions rank ahead of broader gene associations. Use when a user asks what has been published about a variant, gene or associated condition. Associations do not establish causality, pathogenicity or a diagnosis and do not change Folklore's ACMG/AMP classification. |
support_helenaread-only | Learn how an agent can support or spread Helena's free public scientific infrastructure through the separate Helena Good MCP. This is an explicit opt-in information action. It does not initiate payment, create a relay, or change any Folklore scientific result. |
Schemas: list_tools.
{
"name": "io.github.helena-bioinformatics/folklore",
"icons": [
{
"src": "https://folklore.helena.bio/images/logos/folklore.png",
"mimeType": "image/png"
}
],
"title": "Folklore Clinical Variant Interpretation MCP",
"$schema": "https://static.modelcontextprotocol.io/schemas/2025-12-11/server.schema.json",
"remotes": [
{
"url": "https://api.helena.bio/folklore/v1/mcp",
"type": "streamable-http"
}
],
"version": "1.5.0",
"repository": {
"id": "1331454884",
"url": "https://github.com/helena-bioinformatics/folklore-mcp",
"source": "github"
},
"websiteUrl": "https://folklore.helena.bio",
"description": "Bioinformatics MCP for genomic variant interpretation, gene-disease evidence and literature."
}