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Cybergenic

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Cancer gene co-occurrence and exclusivity in tumour cohorts, with confound controls and exact tests.

v1.0.0 · active · website · descriptor JSON · versions

An agent can connect right now, no human step.Remote endpoint, no authentication, reachable on the last probe.
Quality96strong
Trust83of 100
Uptime, 30 days100%
Latency p50382 ms

Connect

8 clients · secrets stay placeholders
{
  "mcpServers": {
    "cybergenic": {
      "type": "http",
      "url": "https://cybergenic.im/mcp?via=mcpregistry"
    }
  }
}
claude mcp add --transport http cybergenic https://cybergenic.im/mcp?via=mcpregistry
[mcp_servers.cybergenic]
url = "https://cybergenic.im/mcp?via=mcpregistry"
{
  "$schema": "https://opencode.ai/config.json",
  "mcp": {
    "cybergenic": {
      "type": "remote",
      "url": "https://cybergenic.im/mcp?via=mcpregistry",
      "enabled": true
    }
  }
}
{
  "mcpServers": {
    "cybergenic": {
      "type": "http",
      "url": "https://cybergenic.im/mcp?via=mcpregistry"
    }
  },
  "deeplink": "cursor://anysphere.cursor-deeplink/mcp/install?name=cybergenic&config=eyJ0eXBlIjoiaHR0cCIsInVybCI6Imh0dHBzOi8vY3liZXJnZW5pYy5pbS9tY3A%2FdmlhPW1jcHJlZ2lzdHJ5In0%3D"
}
{
  "servers": {
    "cybergenic": {
      "type": "http",
      "url": "https://cybergenic.im/mcp?via=mcpregistry"
    }
  }
}
{
  "mcpServers": {
    "cybergenic": {
      "httpUrl": "https://cybergenic.im/mcp?via=mcpregistry"
    }
  }
}
extensions:
  "cybergenic":
    enabled: true
    name: "cybergenic"
    type: streamable_http
    uri: "https://cybergenic.im/mcp?via=mcpregistry"
    timeout: 300

Quality 96 / 100strong

protocol88 · weight 25
  • pass
    protocol.modernsupports 2026-07-28 (server/discover)
  • pass
    protocol.statelessanswers without a session
  • pass
    protocol.transportstreamable HTTP
  • warn
    protocol.list_ttltools/list declares ttlMs 0, so clients re-fetch it on every use
authorizationn/a · weight 15
  • n/a
    auth.prm, auth.as_metadata, auth.cimdno remote uses OAuth
  • n/a
    auth.secret_in_urlno templated URL
tool hygiene100 · weight 30
  • pass
    tools.descriptionsevery tool has a description
  • pass
    tools.description_lengthdescriptions are concise
  • pass
    tools.schemasevery tool has an object input schema
  • pass
    tools.annotations9 of 9 tools declare readOnlyHint or destructiveHint
  • pass
    tools.directory_hintsevery tool declares readOnlyHint, destructiveHint, idempotentHint and openWorldHint
  • pass
    tools.token_costabout 3,011 tokens to load every tool
  • pass
    tools.api_dumptools are not a one-to-one API dump
stability100 · weight 15
  • pass
    stability.changes1 tool changes in 30 days
  • pass
    stability.rug_pullno tool changed its meaning under the same name
dependenciesn/a · weight 15
  • n/a
    deps.known_vulns, deps.mcp_sdk_version, deps.resolvableno npm or PyPI package

9 tools, about 3,011 tokens to load them all · tool set 2fc159640812 · tools last changed 2026-10-07 · checked 2026-10-20 23:27 UTC

Tool changes

  • lookup_gene_pairchangeddescription
    before

    Measured co-alteration statistics for two genes in every tumour cohort where Cybergenic's discovery scan tested the pair: tumours with both genes altered against the number expected, odds ratio, p-value and Benjamini-Hochberg q over that cohort's whole family of tested pairs, the confound control applied (molecular subtype, lineage or histology strata, with mutation burden conditioned on), and whether the pair passes the scan's own discovery gates. A direction is stated only where it is significant and consistent, and cohorts are also counted by independent patient source (the two MSK cohorts overlap). Also returns Cybergenic's published findings on the pair with their verdicts and permalinks. Use it to answer whether two genes' driver mutations co-occur or are mutually exclusive in patient tumours. Associations in tumour sequencing, not causal or clinical evidence.

    after · 97% of words in common

    Measured co-alteration statistics for two genes in every tumour cohort where Cybergenic's discovery scan tested the pair: tumours with both genes altered against the number expected, odds ratio, p-value and Benjamini-Hochberg q over that cohort's whole family of tested pairs, the confound control applied (molecular subtype, lineage or histology strata, with mutation burden conditioned on), and whether the pair passes the scan's own discovery gates. A direction is stated only where it is significant, consistent and at least a two-fold odds ratio, and cohorts are also counted by independent patient source (the two MSK cohorts overlap). Also returns Cybergenic's published findings on the pair with their verdicts and permalinks. Use it to answer whether two genes' driver mutations co-occur or are mutually exclusive in patient tumours. Associations in tumour sequencing, not causal or clinical evidence.

Full history: list_changes · trend: quality JSON.

Checks run on what our credential-free, read-only probes observe; tools are never called and no code audit is performed. How it is computed.

Trust 83 / 100

no-repository
provenance55
liveness100
freshness100
hygiene80

+dns-namespace +website +reachable +uptime-100% +updated-23d-ago -no-repository

Derived from observable signals (official registry feed and our own credential-free probes); no code audit performed. How it is computed.

Endpoints

remoteauthreachableuptime 30dp50protocollast ok
https://cybergenic.im/mcp?via=mcpregistry streamable-httpnoneyes100%382 ms2026-07-282026-10-20

Tools (9)

chi_square_testread-onlyPearson chi-square test of independence for an r x c table of counts (2x2 up to 10x10), with Yates' correction for 2x2 tables and the G-test: statistic, degrees of freedom, p-value, expected counts, adjusted residuals, Cramér's V, whether Cochran's rule for the approximation holds, and Fisher's exact test when the table is 2x2. Empty rows and columns are dropped and reported.
fdr_correctionread-onlyMultiple-testing correction for a list of p-values: Benjamini-Hochberg q-values and Benjamini-Yekutieli, Holm, Hochberg and Bonferroni adjusted p-values, the number of discoveries at alpha for each method, and the Benjamini-Hochberg cutoff rank. Pass family_size when more tests were run than the p-values supplied (for example only the top hits were kept). Up to 10,000 p-values per call; the same implementation as cybergenic.im/tools/fdr-correction, verified against R p.adjust and statsmodels.
fisher_exact_testread-onlyFisher's exact test for a 2x2 table [[a, b], [c, d]]: two-sided and both one-sided p-values (computed in log space, so a tiny p keeps its real exponent), the sample odds ratio, and the conditional maximum-likelihood odds ratio with its exact confidence interval (what R's fisher.test reports). For two genes: a = tumours with both altered, b = gene A only, c = gene B only, d = neither. Up to 100,000 observations. The same implementation as cybergenic.im/tools/fisher-exact-test.
gene_partnersread-onlyThe genes whose driver mutations co-occur with, or are mutually exclusive with, a given gene in patient tumours, strongest first by Benjamini-Hochberg q, from every pair Cybergenic's discovery scan tested: one row per partner and independent patient source, with the tumours, observed and expected co-alteration and the odds ratio. By default only pairs the scan's own gates keep (significant, a real effect size, a consistent direction, enough tumours); set passing_only to false to include significant pairs that fail a gate. Filter by cancer, direction and q threshold. Use it to survey a gene's co-alteration landscape before looking up a specific pair. Associations in tumour sequencing, not causal or clinical evidence.
get_findingread-onlyThe full record of one Cybergenic finding, by id or permalink: what was measured and in which cohort, the statistics (the 2x2 table, odds ratio, p and q), the verdict and why, the confound checks, how many papers mention the genes together, CRISPR dependency and survival facts when measured, the prediction locked for it in the hash-chained registry, the same question in other cohorts, and a citation. The hypothesis text is a model-written annotation, not evidence.
get_track_recordread-onlyCybergenic's live track record: how many predictions it has locked in its hash-chained registry before re-testing them, how many replicated in an independent cohort against matched controls (including the less-studied-pair subset), and how many findings currently pass every check as both strong and overlooked. Read it before describing how reliable the engine is; it states its own limits, including whether the replication comes from well-known biology.
lookup_gene_pairread-onlyMeasured co-alteration statistics for two genes in every tumour cohort where Cybergenic's discovery scan tested the pair: tumours with both genes altered against the number expected, odds ratio, p-value and Benjamini-Hochberg q over that cohort's whole family of tested pairs, the confound control applied (molecular subtype, lineage or histology strata, with mutation burden conditioned on), and whether the pair passes the scan's own discovery gates. A direction is stated only where it is significant, consistent and at least a two-fold odds ratio, and cohorts are also counted by independent patient source (the two MSK cohorts overlap). Also returns Cybergenic's published findings on the pair with their verdicts and permalinks. Use it to answer whether two genes' driver mutations co-occur or are mutually exclusive in patient tumours. Associations in tumour sequencing, not causal or clinical evidence.
odds_ratio_relative_riskread-onlyEffect sizes for a 2x2 table [[a, b], [c, d]] whose rows are two groups and whose columns are outcome yes and no: the odds ratio (Woolf interval, and the conditional exact interval), the relative risk (Katz interval), the risk difference (Newcombe interval) and the number needed to treat, at the chosen confidence level, plus Fisher's exact p. A zero cell applies the Haldane-Anscombe correction to the Woolf and Katz estimates, and the result says so.
search_findingsread-onlySearch Cybergenic's published findings: gene-pair co-occurrence and mutual exclusivity, survival associations, CRISPR gene dependencies and single-gene leads, each with the verdict the engine measured (strengthened, weakened, inconclusive, artifact risk or novel lead) and the reason for it. The query works like the site's search: exact gene symbols, cancer names or abbreviations (NSCLC, CRC, PDAC, TNBC), or both, and every term must match. Returns permalinks to cite and ids for get_finding.

Schemas: list_tools.

Similar MCP servers

Official server.json
{
  "name": "im.cybergenic/mcp",
  "icons": [
    {
      "src": "https://cybergenic.im/brand/icon.svg",
      "sizes": [
        "any"
      ],
      "mimeType": "image/svg+xml"
    }
  ],
  "title": "Cybergenic",
  "$schema": "https://static.modelcontextprotocol.io/schemas/2025-12-11/server.schema.json",
  "remotes": [
    {
      "url": "https://cybergenic.im/mcp?via=mcpregistry",
      "type": "streamable-http"
    }
  ],
  "version": "1.0.0",
  "websiteUrl": "https://cybergenic.im/connect?utm_source=mcpregistry&utm_medium=listing&utm_campaign=mcp-agent-channel",
  "description": "Cancer gene co-occurrence and exclusivity in tumour cohorts, with confound controls and exact tests."
}