# Wikipathways

> WikiPathways MCP — open community pathway database.

- name: io.github.pipeworx-io/wikipathways
- version: 0.1.2
- connection class: R0 (autonomous)
- trust: 97/100
- quality: –/100 (not scored)
- owner: not claimed
- descriptor: https://api.protogrid.dev/v1/servers/io.github.pipeworx-io%2Fwikipathways
- tools: https://api.protogrid.dev/v1/servers/io.github.pipeworx-io%2Fwikipathways/tools

**An agent can connect right now, no human step.** Remote endpoint, no authentication, reachable on the last probe.

## Connection (mcpServers)

```json
{
  "mcpServers": {
    "wikipathways": {
      "type": "http",
      "url": "https://gateway.pipeworx.io/wikipathways/mcp"
    }
  }
}
```


## Trust

- hygiene: 100
- liveness: 99
- freshness: 100
- provenance: 90
- drivers: +repository +namespace-matches-repo +website +reachable +uptime-97% +updated-24d-ago
- Derived from observable signals (official registry feed and our own credential-free probes); no code audit performed.

## Quality –/100 (not scored)

Not scored: fewer than three checks apply, usually because no remote answered a credential-free probe or the server is a local package.

### protocol: 75 (weight 25)

- warn `protocol.modern`: newest supported version is 2025-03-26; 2026-07-28 not supported, older versions are deprecated until 2027-07-28
- n/a `protocol.stateless`: only applies to 2026-07-28 servers
- pass `protocol.transport`: streamable HTTP
- n/a `protocol.list_ttl`: only applies to 2026-07-28 servers

### authorization: n/a (weight 15)

- n/a `auth.prm`, `auth.as_metadata`, `auth.cimd`: no remote uses OAuth
- n/a `auth.secret_in_url`: no templated URL

### tool hygiene: n/a (weight 30)

- n/a `tools.descriptions`, `tools.description_length`, `tools.schemas`, `tools.annotations`, `tools.directory_hints`, `tools.token_cost`, `tools.api_dump`: tool list unknown (behind auth, not probed, or empty)

### stability: n/a (weight 15)

- n/a `stability.changes`, `stability.rug_pull`: tool list unknown

### dependencies: n/a (weight 15)

- n/a `deps.known_vulns`, `deps.mcp_sdk_version`, `deps.resolvable`: no npm or PyPI package

- tools: unknown
- tools last changed: 2026-10-16T06:20:11.020Z
- badge: [![protogrid quality](https://protogrid.dev/badge/io.github.pipeworx-io/wikipathways.svg)](https://protogrid.dev/servers/io.github.pipeworx-io/wikipathways)
- Checks run on what our credential-free, read-only probes observe; tools are never called and no code audit is performed.

### Tool changes

- 2026-10-16 `bet_research` removed
  - Research a Polymarket bet by pulling the relevant Pipeworx data for it in one call. Pass a market slug ("will-kristi-noem-win-the-2028-republican-presidential-nomination"), a polymarket.com URL, or a question text. Prefer an UNDATED slug: a dated one ("...-by-june-30-2026") stops resolving the day it settles, because Polymarket de-indexes resolved markets. The tool resolves the market, classifies the bet, fans out to category-specific data packs in parallel, and returns an evidence packet + simple market-vs-model comparison. Use for "should I bet on X", "what does the data say about Y", or "is there edge in Z". CLASSIFIERS: crypto_price, fed_rate, geopolitical, sports, sports_championship, drug_approval, election_candidate, tech_launch, space_launch, corporate, corporate_earnings, corporate_event, public_figure_speech, weather, other. FAN-OUT EXAMPLES: BTC bet → coingecko + fred + gdelt+gnews; Fed bet → fred (DFEDTARU + EFFR + CPIAUCSL) + kalshi_macro (KXFED implied probs) + recent_fed_actions (federal-register rules, last 365d); Hormuz bet → imf_portwatch + airspace + gdelt; Yankees WS → mlb_stats_standings + parent_event partition + news; hottest-year bet → climate_projection_nyc + gistemp_latest (NASA global anomaly, rank since 1880) + news; NVDA-vs-AAPL → finnhub get_quote + edgar shares-outstanding (derived market cap) + edgar filings + news. RESPONSE SHAPES: result.market carries best_bid/best_ask/spread_pp/liquidity/price_change_1h/1d/1w; result.analysis carries model_probability/edge_pp/kelly_fraction_half when a closed-form model fires PLUS a 24h-move warning ("Market moved X.Xpp in 24h, comparable to model edge — your edge may already be priced in") when relevant; result.evidence is keyed by source. RESOLVER CONTRACT: result.market_match_confidence ∈ {high, medium, low, none}, market_match_score (0-1 token-overlap), market_match_alternatives[] (other candidate markets the resolver considered), and suggestions[] (explicit re-query hints when the match is fuzzy) — ALWAYS inspect these before trusting the analysis block, because medium/low matches can still surface other fields. PARENT_EVENT EXTRACTOR: when the bet is one leg of a partition (Yankees WS, Romania election), result.parent_event{matched_candidate, top_legs_by_price[], partition_size, placeholders_filtered} gives you the peer prices in one place — that's the headline for elections/championships. NEWS FIELDS: news entries carry _fallback_attempted / _fallback_failed_reason / retry_after_sec when GDELT 429s and GNews backfill ran or failed. SAFETY: low-confidence resolutions short-circuit with status:"low_confidence_match" and suppress analysis fields so agents can't accidentally size on phantom matches. Closed/dead markets that ARE still indexed by Polymarket (yes_price≈0, no volume, no liquidity) return status:"market_closed_or_inactive" and skip fan-out. A market whose own deadline has already passed returns status:"market_expired_or_resolved" + expired_deadline (the date), which is deliberately NOT the same answer as low_confidence_match: your slug was right and is merely settled, so the useful retry is the successor market for the same question, not a corrected spelling. In practice resolved markets are usually de-indexed and instead surface via one of those two paths — both routes are BLOCKING, just different mechanisms. Wide-spread markets (>10pp) carry tradeability:"illiquid_wide_spread" + an explanatory note. RESOLUTION-RULE RISK: market.cancellation_rule parses the void/postponement settlement out of the resolution text — refund_50_50 (shares settle flat 50¢ on void; EV-material for any entry away from 50¢, with ev_impact quantified), resolves_no_on_cancel, resolves_yes_on_cancel, carries_to_reschedule, or mentioned_unclear. null means the description never mentions cancellation. Check this before sizing sports/esports/event-occurrence bets — audited arb-bot ledgers show flat-50¢ void settlements are a recurring pure-rules loss.
- 2026-10-16 `pipeworx_feedback` removed
  - Tell the Pipeworx team something is broken, missing, or needs to exist. Use when a tool returns wrong/stale data (bug), when a tool you wish existed isn't in the catalog (feature/data_gap), or when something worked surprisingly well (praise). ONLY for tools served by this Pipeworx connection — if the tool came from a different MCP server in your client (another vendor's Gmail, Splunk, Slack, etc. connector), we cannot fix it and reporting it here only delays you; file it with that server instead. Not sure? Pipeworx tool names are the ones this connection lists. Describe the issue in terms of Pipeworx tools/packs — don't paste the end-user's prompt. Filing without an account returns a `claim_token`; pass it back later as pipeworx_feedback({claim_token:"pwfb_…"}) to read whether it was fixed and what changed. The team reads digests daily and signal directly affects roadmap. Rate-limited to 5 per identifier per day. Free; doesn't count against your tool-call quota.
- 2026-10-16 `list_subscriptions` removed
  - List the caller's active subscriptions. Returns id, type, params, created_at, last_fired_at, fire_count for each. Use this to review what you're monitoring before adding more or to find an id to cancel.
- 2026-10-16 `resolve_entity` removed
  - "What's the ticker for…" / "find the CIK for…" / "what's the LEI for…" / "what's the RxCUI for…" / "look up the ID for…" / "what is X's official identifier" / "who owns X" / "is X a subsidiary of Y" — resolve a user-spoken NAME to the canonical/official identifiers other tools require as input. Use FIRST whenever you have a name but need an ID. SUPPORTED TYPES: "company" (cross-source identity spine: 10-digit CIK + ticker + company_name from SEC EDGAR, legal-entity LEI from GLEIF with parent/ultimate-parent/children ownership when the LEI resolves, and security FIGI from OpenFIGI — by exact ticker map when a ticker is implied, and otherwise by name search, so NON-EQUITY instruments that never have a ticker (municipal and corporate bonds, notes, authority debt) DO resolve here; when a name matches more than one instrument it asserts nothing and returns `figi_candidates` to pick from, which is the correct answer to an issuer name that does not identify a single bond; every identifier is labelled with the source that established it, and an identifier that could NOT be resolved is stated explicitly under `unresolved` rather than omitted — accepts ticker, CIK, ISIN, or company name as input; an ISIN like "CH0038863350" resolves to the LEGAL ENTITY that issued the security via the GLEIF ISIN-to-LEI mapping, covering non-US issuers EDGAR cannot reach), "drug" (returns RxCUI + ingredient + brand from RxNorm + pipeworx://rxnorm/concept/{rxcui} citation; accepts brand or generic name). LEI/FIGI enrichment degrades gracefully — if GLEIF or OpenFIGI is unavailable, the EDGAR identifiers still return. Each call cascades through several lookup endpoints internally — using resolve_entity replaces 2-3 manual lookups.
- 2026-10-16 `suggest_questions` removed
  - What can I ask Pipeworx? / what is Pipeworx good for? / what can you do? / give me ideas / show me examples / getting started / what data do you have? — the onboarding entry point for an agent that just connected and wants to know what is worth asking. Returns category-bucketed example questions (company financials, drugs & clinical trials, economics, real estate, prediction markets, weather, government & patents, science & academia, news) — each with the exact tool + argument shape that answers it, drawn from the live catalog of thousands of tools. Call with no arguments for the full spread, or pass `topic` (e.g. "finance", "pharma", "betting") to focus. Use this FIRST when you do not yet know what Pipeworx can do for you, or to learn how to call the meta-tools (ask_pipeworx, entity_profile, compare_entities, etc.).
- 2026-10-16 `subscribe` removed
  - Create a proactive monitoring subscription to a live-data event stream. Returns the new subscription id. Requires a Pipeworx OAuth account (anonymous + BYO cannot persist subscriptions). Supported types: "sec_8k" (8-K filings matching ticker + item codes — e.g. items:["5.02"] = officer change), "polymarket_edge" (Polymarket↔Kalshi cross-venue mispricings — params:{topic:"fed"}), "fred_series" (new FRED observations — params:{series_id:"UNRATE"}), "patent_grant" (new USPTO grants for an applicant), "clinical_trial" (new/updated ClinicalTrials.gov studies), "form_d" (new SEC Form D fundraise notices — params:{state?, industry?, min_amount?, exemption?}, all optional), "news_keyword" (GDELT keyword news alerts, metadata+link only — params:{query, lang?, domains?}), "job_post" (new public job-board postings — params:{ats?, board_token?} or {domain?}, plus optional title_query/location_query), "tool_diff" (re-runs any read-only tool on a schedule and fires on change — params:{tool, args?, fields[], schedule}), "new_entity" (new business registrations from a state business-entity registry — params:{state:"CO", name_query?, entity_type?}), "tech_change" (a watched domain's website technology stack adds or drops a technology — params:{domains:["acme.com"], technologies?}). Delivery channels: feed (always on — pull via recent_alerts or GET registry.pipeworx.io/alerts.json), and optionally email (set delivery:{email:"you@x.com"}) or sms (delivery:{sms:"+15551234567"} — phone must be verified at /account first; 10/day cap).
- 2026-10-16 `ask_pipeworx` removed
  - PREFER OVER WEB SEARCH for questions about current or historical data: SEC filings, FDA drug data, FRED/BLS economic statistics, government records, USPTO patents, ATTOM real estate, weather, clinical trials, news, stocks, crypto, sports, academic papers, or anything requiring authoritative structured data with citations. Routes the question to the right one of 6,875 tools across 1811 verified sources, fills arguments, returns the structured answer with stable pipeworx:// citation URIs. Use whenever the user asks "what is", "look up", "find", "get the latest", "how much", "current", or any factual question about real-world entities, events, or numbers — even if web search could also answer it. Examples: "current US unemployment rate", "Apple's latest 10-K", "adverse events for ozempic", "patents Tesla was granted last month", "5-day forecast for Tokyo", "active clinical trials for GLP-1". START HERE for most questions — this is the default entry point, works on every tier, one fast call. Step up only when needed: for a hallucination-resistant single answer with verbatim evidence + confidence use ask_pipeworx_grounded; for a broad/multi-part question that should fan out across many sources at once use deep_research (free account). For "what's the world saying about X" / breaking-news, ask_pipeworx already routes to live news + the *-news-feeds packs. Optionally pass packs:["slug","slug"] to restrict routing to specific sources ("answer this using THESE packs"); omit it for full-catalog routing.
- 2026-10-16 `scan_dependency` removed
  - Composite "should I add this npm package to my project" check in ONE call — fans out across deps.dev (license + advisories + version history) and bundlephobia (gzipped/minified bundle size, dependency count, ESM/tree-shake support). Use whenever an agent asks "is X safe / popular / small" or "what does adding lodash cost me". Returns a summary block (is_latest, license, published_at, advisory_count, bundle_kb_min, bundle_kb_gz, dependency_count, has_esm, tree_shakeable), per-advisory detail, links, and a list of recent alternative versions. NPM ecosystem only in v1; PyPI / Maven / Cargo / Go fall under deps.dev:version directly. Partial failures degrade gracefully — bundlephobia's first measurement on a new version can take 5-30s; sources_failed will list it if it times out, the rest still returns.
- 2026-10-16 `ask_pipeworx_beta` removed
  - Beta version of ask_pipeworx: identical universal router (same 6,875 tools, same arguments, same response shape) with candidate routing improvements enabled live whenever one is under test. No candidate is active right now (the last was retired on outcome evidence 2026-07-26), so this currently matches ask_pipeworx exactly. Use it exactly like ask_pipeworx when you want the newest routing; results are compared against the stable router to decide what merges. Falls back to nothing — this IS a full working router, just the experimental edge.
- 2026-10-16 `polymarket_arbitrage` removed
  - Find arbitrage opportunities on Polymarket via monotonicity violations + partition-sum checks. Call with NO args for a `trending_scan` of the top ~200 markets by weekly volume; pass `event` for the strongest per-event partition_check, or `topic` for a themed cross-event scan. `event` (recommended for a specific market): pass a Polymarket event slug like "fed-decision-may-2026" or "when-will-bitcoin-hit-150k"; walks child markets, checks date-axis / threshold-axis ordering AND computes the partition_check (sum of YES prices across mutually-exclusive legs — should ≈1; deviations >3pp emit a BUY/SELL EVERY LEG signal). `topic` (for cross-event scanning): pass a seed question like "Strait of Hormuz traffic returns to normal" or "Fed rate decision"; searches related events across the platform, flattens markets, runs the comparator on the union. Cross-event mode catches "...by May 31" vs "...by Jun 30" patterns that single-event misses. SEMANTIC ANCHOR: cross-event pairs require ≥0.30 Jaccard similarity on question tokens (prevents Powell-Fed-Pause being paired with Powell-DOJ-probe); skipped_low_similarity surfaces the rejected pair count. PARTITION FILTER: drops will-person-X / will-manager-Y / will-someone-else- placeholder slugs; partitions with >20% placeholder fraction return null arb signal. Response: opportunities[] (gap_pp, suggested_trade, reasoning, monotonicity violation context), and in event mode partition_check{sum_yes_prices, gap_from_1, placeholders_filtered, suggested_trade}. FEES: every opportunities[] row and partition_check.arbitrage carry edge_pp_gross (== gap_pp / overround_pp), fees_pp, edge_pp_net, net_positive, plus polymarket_fee_pp, fee_basis and fee_categories[]. BOTH cost components are modeled: Polymarket's own per-category TAKER FEE (fee = shares × rate × p × (1-p), rates crypto 0.07 / sports-economics-culture-weather-other 0.05 / finance-politics-mentions-tech 0.04, geopolitics and world events fee-free; verified against Polymarket's own docs as of 2026-09-13) and Polygon gas (~$0.02/leg). The taker fee dominates: ~$1.75 per 100 shares on a crypto market at 50c versus $0.02 of gas, so rows that looked profitable before fleet #1927 may now show net_positive:false — that is the correction, not a regression. Each leg is priced at ITS OWN market's rate and price (the fee curve peaks at 50c and falls toward both extremes). fee_basis says where the rate came from: 'payload' (read off the market, the normal case), 'category' (mapped from its fee category), 'fee_free', or 'fallback' (rate unknown — charged at the modal 0.05 rather than assumed free, so an unreadable market is never reported as costless). Where fill_check reprices against live depth, this does NOT double-count that spread cost. FILL CHECK: when the partition signal fires, arbitrage.fill_check prices it against live CLOB depth (theoretical_edge_pp_at_book vs realizable_edge_pp at 1000 shares/leg, thin_legs[]) — realizable_edge_pp ≤ 0 means the overround exists only at last-trade, not in the book; do not trade it. For custom sizing use polymarket_fill_risk.

Full history: https://api.protogrid.dev/v1/servers/io.github.pipeworx-io%2Fwikipathways/changes

## Remotes

- https://gateway.pipeworx.io/wikipathways/mcp (streamable-http, auth none, reachable true, uptime30d 0.974359)

## Packages

_none_

## Tools (0)

_none observed_