# Hpo Api

> HPO API MCP.

- name: io.github.pipeworx-io/hpo-api
- version: 0.1.2
- connection class: R0 (autonomous)
- trust: 95/100
- quality: –/100 (not scored)
- owner: not claimed
- descriptor: https://api.protogrid.dev/v1/servers/io.github.pipeworx-io%2Fhpo-api
- tools: https://api.protogrid.dev/v1/servers/io.github.pipeworx-io%2Fhpo-api/tools

**An agent can connect right now, no human step.** Remote endpoint, no authentication, reachable on the last probe.

## Connection (mcpServers)

```json
{
  "mcpServers": {
    "hpo-api": {
      "type": "http",
      "url": "https://gateway.pipeworx.io/hpo-api/mcp"
    }
  }
}
```


## Trust

- hygiene: 100
- liveness: 99
- freshness: 100
- provenance: 85
- drivers: +repository +namespace-matches-repo +website -thin-description +reachable +uptime-98% +updated-24d-ago
- Derived from observable signals (official registry feed and our own credential-free probes); no code audit performed.

## Quality –/100 (not scored)

Not scored: fewer than three checks apply, usually because no remote answered a credential-free probe or the server is a local package.

### protocol: 75 (weight 25)

- warn `protocol.modern`: newest supported version is 2025-03-26; 2026-07-28 not supported, older versions are deprecated until 2027-07-28
- n/a `protocol.stateless`: only applies to 2026-07-28 servers
- pass `protocol.transport`: streamable HTTP
- n/a `protocol.list_ttl`: only applies to 2026-07-28 servers

### authorization: n/a (weight 15)

- n/a `auth.prm`, `auth.as_metadata`, `auth.cimd`: no remote uses OAuth
- n/a `auth.secret_in_url`: no templated URL

### tool hygiene: n/a (weight 30)

- n/a `tools.descriptions`, `tools.description_length`, `tools.schemas`, `tools.annotations`, `tools.directory_hints`, `tools.token_cost`, `tools.api_dump`: tool list unknown (behind auth, not probed, or empty)

### stability: n/a (weight 15)

- n/a `stability.changes`, `stability.rug_pull`: tool list unknown

### dependencies: n/a (weight 15)

- n/a `deps.known_vulns`, `deps.mcp_sdk_version`, `deps.resolvable`: no npm or PyPI package

- tools: unknown
- tools last changed: 2026-10-20T06:38:19.325Z
- badge: [![protogrid quality](https://protogrid.dev/badge/io.github.pipeworx-io/hpo-api.svg)](https://protogrid.dev/servers/io.github.pipeworx-io/hpo-api)
- Checks run on what our credential-free, read-only probes observe; tools are never called and no code audit is performed.

### Tool changes

- 2026-10-20 `gene_diseases` removed
  - "What diseases is gene [NCBIGene:N] associated with" / "diseases linked to gene [X]" / "TP53 disease associations" — fetch diseases associated with a gene ID (NCBIGene:N format). Use for gene-to-disease lookups in rare-disease research, variant prioritization. Example ID: NCBIGene:7157 (TP53).
- 2026-10-20 `term_descendants` removed
  - "All phenotypes under [HP:N]" / "full subtree of [HPO term]" — transitive descendants (children, grandchildren, …) of an HPO term. Use for exhaustive coverage (e.g. "every cardiac phenotype" via descendants of HP:0001626).
- 2026-10-20 `term_parents` removed
  - "What broader phenotype is [HP:N] under" / "parent term of [HPO ID]" — direct parents of an HPO term in the ontology graph. Use to walk up to a more general phenotype class.
- 2026-10-20 `term_children` removed
  - "More specific HPO phenotypes under [HP:N]" / "child terms of [phenotype]" — direct children of an HPO term in the ontology graph. Use to narrow from a general phenotype (e.g. "Abnormality of the nervous system") to specifics (seizures, ataxia, etc).
- 2026-10-20 `search` removed
  - "HPO term for [symptom]" / "phenotype code for [clinical sign]" / "find HPO IDs about [feature]" / "what's the HPO for seizures / autism / short stature" — text search the Human Phenotype Ontology (HPO). Returns ranked terms with HP: IDs. Use to map clinical descriptions to standard ontology terms for rare-disease workups, genomics, or clinical phenotype databases.
- 2026-10-20 `recall` removed
  - Retrieve a value previously saved via remember, or list all saved keys (omit the key argument). Use to look up context the agent stored earlier — the user's target ticker, an address, prior research notes — without re-deriving it from scratch. Scoped to your identifier (anonymous IP, BYO key hash, or account ID). Pair with remember to save, forget to delete.
- 2026-10-20 `remember` removed
  - Save data the agent will need to reuse later — across this conversation or across sessions. Use when you discover something worth carrying forward (a resolved ticker, a target address, a user preference, a research subject) so you don't have to look it up again. Stored as a key-value pair scoped by your identifier. Authenticated users get persistent memory; anonymous sessions retain memory for 24 hours. Pair with recall to retrieve later, forget to delete.
- 2026-10-20 `scan_competitor_ai_presence` removed
  - Compare AI visibility across multiple entities side-by-side. Probes each entity (your brand + N competitors) with ai_visibility_check, ranks by score, surfaces which is most/least recognized. Useful for competitive AI-marketing audits: "does Claude know about us as well as our competitors?". Returns ranked list with score, confidence, signal density per entity.
- 2026-10-20 `ai_visibility_check` removed
  - Probe one or more LLMs for what they know about a business / brand / product / topic and score visibility (0-100) per model. Default model is Workers AI Llama-3.3-70b (free); pass `_apiKey` to also probe Anthropic (BYO key — you pay Anthropic directly for those calls). Returns per-model {score, confidence, signals, raw_response} + a combined view. Useful for AI-marketing audits, pre-launch brand checks, competitive monitoring.
- 2026-10-20 `suggest_questions` removed
  - What can I ask Pipeworx? / what is Pipeworx good for? / what can you do? / give me ideas / show me examples / getting started / what data do you have? — the onboarding entry point for an agent that just connected and wants to know what is worth asking. Returns category-bucketed example questions (company financials, drugs & clinical trials, economics, real estate, prediction markets, weather, government & patents, science & academia, news) — each with the exact tool + argument shape that answers it, drawn from the live catalog of thousands of tools. Call with no arguments for the full spread, or pass `topic` (e.g. "finance", "pharma", "betting") to focus. Use this FIRST when you do not yet know what Pipeworx can do for you, or to learn how to call the meta-tools (ask_pipeworx, entity_profile, compare_entities, etc.).

Full history: https://api.protogrid.dev/v1/servers/io.github.pipeworx-io%2Fhpo-api/changes

## Remotes

- https://gateway.pipeworx.io/hpo-api/mcp (streamable-http, auth none, reachable true, uptime30d 0.982906)

## Packages

_none_

## Tools (0)

_none observed_